Agenda

Wednesday, February 7, 2024
7:30 a.m.‒6:00 p.m. Registration and Information
9:00‒10:00 a.m. Poster Session #1
10:00 a.m.‒12:00 p.m. Plenary Session
    10:00‒10:10 a.m. Welcome
Nora Volkow, M.D., Director, National Institute on Drug Abuse (NIDA)
    10:10‒10:30 a.m. Toward Evidence-Based Care for All
Lawrence A. Tabak, D.D.S., Ph.D., Principal Deputy Director, National Institutes of Health
    10:30‒11:15 a.m. Building Sustainable Research-Practice Partnerships:
Insights From the Justice Community Opioid Innovation Network (JCOIN)
  • Facilitator – Tisha Wiley, Ph.D., NIDA
  • Presenters
    • Michele Staton, Ph.D., University of Kentucky
    • Katherine Marks, Ph.D., Kentucky Department for Behavioral Health
    • Elizabeth Evans, Ph.D., M.A., University of Massachusetts Amherst
    • Ed Hayes, Franklin County (Massachusetts) Sheriff’s Office
    11:15 a.m.‒12:00 p.m. Empowering Open Science Practices:
The HEAL Data Ecosystem
  • Facilitator – Jessica Mazerik, Ph.D., National Institute of Neurological Disorders and Stroke (NINDS)
  • Panelists:
    • Laura Simons, Ph.D., Stanford University School of Medicine
    • Charlie Knott, M.P.A., RTI International
    • Maryann Martone, Ph.D., University of California San Diego
12:00‒1:30 p.m. Lunch (on your own)
Lived and Living Experience & Community Networking Session
This networking session is open to anyone with lived or living experience and community organizations that partner with HEAL-funded projects, as well as pain and addiction advocacy groups. Share experiences, foster connections, and engage in dialogue on patient and community engagement in research.
1:30‒2:45 p.m. Plenary Session
    1:45–2:00 p.m. HEAL vs. Pain: What Do We Have to Do? How Best to Do It?
Walter Koroshetz, M.D., Director, NINDS
    1:45‒2:00 p.m. Scientific Strategies to Address Disparities in the Overdose Crisis
Nora Volkow, M.D., Director, NIDA
    2:00–2:45 p.m. HEAL Leadership Roundtable: Looking to the Future
  • Moderators - Walter Koroshetz, M.D., Director, NINDS, and Nora Volkow, M.D., Director, NIDA
  • Panelists:
    • Lindsey Criswell, M.D., M.P.H., D.Sc., Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases
    • Helene Langevin, M.D., Director, National Center for Complementary and Integrative Health (NCCIH)
    • Joni Rutter, Ph.D., Director, National Center for Advancing Translational Sciences
2:45‒3:00 p.m. Break
3:00‒4:45 p.m. Concurrent Scientific Symposia and Discussion Sessions
Symposium and Discussion #1
Advancing Translation: Human-Based Research Models
  • Facilitator – Michael Oshinsky, Ph.D., NINDS
  • Presenters:
    • Harmonized Cross-Species Cell Atlases of Trigeminal and Dorsal Root Ganglia
      William Renthal, M.D., Ph.D., Brigham and Women’s Hospital, Harvard Medical School
    • Defining Mechanisms of Pain Relief Associated With Dorsal Root Ganglion and Spinal Cord Stimulation
      H. Richard Koerber, Ph.D., University of Pittsburgh
    • Novel Electrophysiological and Ultrasound Biomarkers for Trigger Point Assessment
      Askhat Mukushev, M.D., Beth Israel Deaconess Medical Center
    • Human IPSC-Derived PreBötC-Like Neurons and Development of an Opiate Overdose and Recovery Model
      Xiufang (Nadine) Guo, Ph.D., University of Central Florida
Symposium and Discussion #2
Creative Therapeutic Strategies
  • Facilitator – Alex Tuttle, Ph.D., NCCIH
  • Presenters:
    • Bacteriophage Virus-Like Particle-Based Vaccines Against Opioids
      Isabella Romano, University of New Mexico Health Sciences Center
    • Clinical Translation of Ultrasonic Ketamine Uncaging for Precision Pain Pharmacotherapy
      Raag Airan, M.D., Ph.D., Stanford University
    • Preclinical Development Update on Disease Modifying Analgesia With CA8 Gene Therapy
      Roy Levitt, M.D., Adolore BioTherapeutics, Inc., University of Miami Miller School of Medicine
Symposium and Discussion #3
Data-Driven Decision Making in the HEALing Communities Study
  • Facilitator – Jennifer Villani, Ph.D., NIDA
  • Presenters:
    • Setting the Stage: An Approach to Data Access, Visualization, and Engagement in the Massachusetts Site of the HEALing Communities Study?
      Carly Bridden, M.A., M.P.H., Boston Medical Center
    • CASE STUDY 1 – Engaging an Urban Massachusetts Community in Data Walks to Understand Service Gaps and Opportunities to Prevent Opioid Overdose Deaths
      Rebecca Smeltzer, M.P.H., Boston Medical Center
    • CASE STUDY 2 – Engaging People With Lived Opioid Use Experience From Rural Massachusetts in Photovoice to Understand Factors Fueling the Local Opioid Epidemic
      Peter Balvanz, M.P.H., Boston Medical Center
    • CASE STUDY 3 – Engaging Community-Based Organizations and Community Coalition Members in Process Evaluation With Web-Based Monitoring Reports
      Sarah Kosakowski, M.P.H., Boston Medical Center
Symposium and Discussion #4
Equity-Focused Pain Management
  • Facilitator – Cheryse Sankar, Ph.D., NINDS
  • Presenters:
    • You Get Tired of Saying, “This Doesn’t Work”: A Qualitative Study of Chronic Pain Treatment Experiences Among Older Spanish-Speaking Latinos in a Community Setting
      Natalia Giraldo-Santiago, Ph.D., LCSW, Massachusetts General Hospital
    • Addressing Chronic Pain Inequities Through Multimodal Care in Primary Care Safety-Net Clinics
      Ariana Thompson-Lastad, Ph.D., University of California San Francisco
    • Providing Telehealth Physical Therapy in Rural Communities: Lessons Learned From Two Pragmatic Trials
      Julie Fritz, Ph.D., P.T., University of Utah
Symposium and Discussion #5
Pragmatic Implementation Science Tools to Enhance the Salon A-D Impact of Your Research
  • Facilitators – Heather Gotham, Ph.D., Stanford University, and Tamara Haegerich, Ph.D., NIDA
  • Presenters:
    HEAL Data2Action Research Adoption Support Center Tools:
    • Evaluating the “Implementability” Potential of an Intervention, Program, or Service
      Heather Gotham, Ph.D., Stanford University
    • Meaningfully Engaging and Integrating Partners Into the Research Process
      Terrinieka Powell, Ph.D., Johns Hopkins Bloomberg School of Public Health
    • Understanding the Context in Which Interventions Are Implemented
      Cecelia Calhoun, M.D., M.P.H.S., M.B.A., Yale School of Medicine
    • Documenting Strategies That Support Implementation of Effective Interventions
      Bryan Garner, Ph.D., Ohio State University College of Medicine
    • Integrating Implementation Outcomes Into Effectiveness Studies
      William Becker, M.D., Yale School of Medicine, VA Connecticut Healthcare System
4:45‒5:00 p.m. Break
5:00‒6:00 p.m. Poster Session #2
Thursday, February 8, 2024
8:00 a.m.‒4:30 p.m. Registration and Information
9:00‒10:45 a.m. Plenary Session
    9:00‒10:00 a.m. Engineering Treatments for Pain and Opioid Use Disorder
  • Facilitator – Will Aklin, Ph.D., NIDA
  • Presenters:
    • Personalized Brain Stimulation for Chronic Pain: A Scientist’s and Patient’s Story
      Prasad Shirvalkar, M.D., Ph.D., and Edward Mowery, University of California San Francisco
    • Nucleus Accumbens Deep Brain Stimulation and Focused Ultrasound for Opioid Use Disorder
      Ali Rezai, M.D., West Virginia University
    10:00‒10:45 a.m. Disentangling the Patient-Level Factors That Drive Chronic Musculoskeletal Pain: Overview of the Back Pain Consortium (BACPAC) Research Program
  • Presenters:
    • Gwendolyn Sowa, M.D., Ph.D., University of Pittsburgh
    • Abel Torres Espin, Ph.D., University of California San Francisco
    • Matt Mauck, M.D., Ph.D., University of North Carolina
    • Kevin Anstrom, Ph.D., M.S., University of North Carolina
10:45‒11:00 a.m. Break
11:00 a.m.‒12:45 p.m. Concurrent Scientific Symposia and Discussion Sessions
Symposium and Discussion #6
Better Together: Community-Informed Research
  • Facilitator – Marcy Fitz-Randolph, D.O., M.P.H., NIDA
  • Presenters:
    • Implementation Intervention Development With Alaska Native and American Indian Community Partners to Culturally Center Delivery of Opioid Use Disorder Treatment
      Aimee Campbell, Ph.D., Columbia University
    • Considerations for Increasing Equity Within Randomized Control Trials for Underserved, Diverse Patient Populations
      Elondra Harr, University of North Carolina School of Medicine
    • Equitable EEG Data Collection in the HBCD Study: The Role of Curly Hair Specialists
      Maria Isabella Natale Castillo and Monique Marsh, Boston Children’s Hospital, Harvard Medical School
Symposium and Discussion #7
Clinical Trial Innovations
  • Facilitator – Geetha Subramaniam, M.D., NIDA
  • Presenters:
    • A Data-Driven Approach to Site Selection: Use of the Trial Innovation Network’s Expression of Interest Process in the HEAL Pain Effectiveness Research Network
      Sarah Nelson and Brooklyn Henderson, R.N., Vanderbilt University Medical Center
    • Rapid Initiation of Naltrexone and Buprenorphine: Findings From the NIDA Clinical Trials Network
      Matisyahu Shulman, M.D., Columbia University
    • Individual Level Risk Prediction of Return-to-Use During Opioid Use Disorder Treatment
      Sean Luo, M.D., Ph.D., Columbia University
Symposium and Discussion #8
Finding Pain Patterns: Role of Biomarkers
  • Facilitator – Ram Arudchandran, Ph.D., NINDS
  • Presenters:
    • Baseline Questionnaires and Longitudinal Headache Diary Data Predict Headache Improvement in Patients With Acute Post-Traumatic Headache Attributed to Mild Traumatic Brain Injury: Balancing Prediction Accuracy and Patient Burden
      Catherine Chong, Ph.D., Mayo Clinic, and Jing Li, Ph.D., Georgia Institute of Technology
    • Imaging Changes in Muscle Structure and Function in Patients With Active Versus Latent Post Stroke Shoulder Pain
      Preeti Raghavan, M.B.B.S., Johns Hopkins Medicine
    • Discovery and Validation of Prognostic and Robust Biosignatures to Predict Recovery or Persistence in Pediatric Pain
      Laura Simons, Ph.D., Stanford University School of Medicine
Symposium and Discussion #9
New Targets and Mechanisms for Pain and Addiction
  • Facilitator – D.P. Mohapatra, Ph.D., NINDS
  • Presenters:
    • Glucagon-Like Peptide-1 Receptor Agonists Reduce Opioid Craving and Seeking Behaviors in Rats and Humans
      Patricia Sue Grigson, Ph.D., M.S., and Scott Bunce, Ph.D., Penn State College of Medicine
    • Targeting a Cryptic Pocket in CB1 Receptors Drives Peripheral and Functional Selectivity
      Susruta Majumdar, Ph.D., Washington University School of Medicine in St. Louis
    • Validation of Neuropilin-1 Receptor Signaling in Nociceptive Processing
      Rajesh Khanna, Ph.D., M.Sc., University of Florida
Symposium and Discussion #10
Prevention in Diverse Communities: How Can Digital Interventions Help?
  • Facilitators – Elvira Elek, Ph.D., RTI International, and Amy Goldstein, Ph.D., NIDA
  • Presenters:
    • Understanding Risk and Protective Factors Associated With Opioid Use and Misuse Risk Groups Among Adolescents and Young Adults in the Emergency Department
      Maureen Walton, Ph.D., M.P.H., University of Michigan
    • The Incorporation of Risk and Protective Factors Into a Digital Intervention to Promote Mental Health and Prevent Opioid Misuse in Adolescents in a School-Based Setting
      Lindsey Bonilla, M.A., Yale University
    • Pain Among Urban Native American Emerging Adults: Exploring Socioeconomic and Cultural Factors
      Elizabeth D’Amico, Ph.D., RAND Corporation
12:45‒2:00 p.m. Lunch (on your own)
2:00‒4:15 p.m. Plenary Session
    2:00‒3:00 p.m. Trailblazing Paths Toward Innovation in HEAL
  • Facilitator – Tamara Haegerich, Ph.D., NIDA
  • Presenters:
    • Beyond Opioids: SRP-001’s Journey From Lab to Clinic as a Non-Opioid Targeting the Brain’s Pain Center
      Hernan Bazan, M.D., FACS, South Rampart Pharma, Inc., Ochsner Health
    • A Biomarker Signature for Predicting Post-Traumatic Headache Persistence
      Catherine Chong, Ph.D., Mayo Clinic
    • www.PainResearchers.com: A Network Empowering Pain Research Through PURPOSE: Fostering Collaborations, Developing Careers, and Supporting Innovations
      Jacob Coverstone, Neurovations Education
    • Leveraging Emergency Departments to Initiate Treatment for Opioid Use Disorder
      Kathryn Hawk, M.D., M.H.S., Yale University
    • Translating Experience Into Practice: Using Human-Centered Design to Engage People With Lived Experience and Improve Equity
      J. Deanna Wilson, M.D., M.P.H., University of Pennsylvania
    3:00‒4:00 p.m. HEAL Connections: Engagement in Action
  • Facilitator – Jessica Hulsey, Addiction Policy Forum
  • Panelists:
    • Denise Bertin-Epp, R.N., M.S., National Association for Children of Addiction
    • Michael Litterer, CHES, CPS, RWJBarnabas Health Institute for Prevention and Recovery
    • Patty McCarthy, M.S., Faces & Voices of Recovery
    • Kate Nicholson, J.D., National Pain Advocacy Center
    • Sarah Wurzburg, Council of State Governments Justice Center
    4:00‒4:15 p.m. Closing Remarks – Reflecting, Recognizing, and Looking Ahead
Helene Langevin, M.D., Director, NCCIH
4:15 p.m. Adjourn
Satellite Meetings - Friday, February 9, 2024
8:00 – 10:00 a.m. Biomarkers of Myofascial Tissues for Clinical Pain Management
  • Organizer: Alex Tuttle, Ph.D., NCCIH
  • Organizer email: alex.tuttle@nih.gov
  • Open to all HEAL Scientific Meeting attendees
8:00 – 11:00 a.m. HEAL Initiative Devices and Technology Satellite Event
  • Organizer: Eric Hudak, Ph.D., NINDS
  • Organizer email: eric.hudak@nih.gov
  • Open to HEAL Scientific Meeting attendees involved in the HEAL Translating Discoveries Into Effective Devices to Treat Pain program, NIDA-led Small Business Programs, NINDS-led Small Business Programs, and any other attendees using devices and technology in their projects
8:00 a.m. – 12:00 p.m. HEAL Biomarker Program Investigators’ Meeting
  • Organizer: Ram Arudchandran, Ph.D., NINDS
  • Organizer email: ramachandran.arudchandran@nih.gov
  • Open to all HEAL Scientific Meeting attendees
8:00 a.m. – 12:00 p.m. Health Equity in Pain Management
  • Organizer: Cheryse Sankar, Ph.D., NINDS
  • Organizer email: cheryse.sankar@nih.gov
  • Open only to HEAL Scientific Meeting attendees involved in this research program
8:30 a.m. – 12:00 p.m. Polysubstance Use and Treatments Initiative Meeting
  • Organizer: Marcy Fitz-Randolph, D.O., M.P.H., NIDA
  • Organizer email: marcy.fitz-randolph@nih.gov
  • Open to all HEAL Scientific Meeting attendees from 8:30–10:00 a.m.
12:00 – 2:00 p.m. Harm Reduction Research Network (HRRN) and JCOIN Cross-Network Meeting
  • Organizer: Julia Zur, Ph.D., NIDA
  • Organizer email: julia.zur@nih.gov
  • Open only to HEAL Scientific Meeting attendees involved in the HRRN and/or JCOIN research programs
1:00 – 3:00 p.m. Consortium on Addiction Recovery Science (CoARS) Meeting
  • Organizer: Sarah Duffy, Ph.D., NIDA
  • Organizer email: duffys@nida.nih.gov
  • Open to all HEAL Scientific Meeting attendees from 1:00–2:00 p.m.

Space is limited for these satellite meetings. If you plan to attend, please reach out to the organizer to check if registration is required. Other HEAL research programs may be hosting satellite meetings. Please reach out to your HEAL program officer for more information.

MEETING INFORMATION

February 7-8, 2024
Bethesda North Marriott Hotel & Conference Center
Bethesda, MD, 20852

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